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management anesthesia anesthesiology intraoperative oncology syndrome tls lysis anaphylaxis arrest blood bradycardia cardiacarrest cardiology cell cooling crisis differential hyperthermia ischaemia
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of Tumor ... 8.0 mg/dL • Potassium ... age and sex) • Cardiac ... hydroxide • Hyperkalemia ... Syndrome #TLS #diagnosis
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Initial workup ... ≥ 8 mg/dL • Potassium ... of the above Treatment ... abnormalities • Cardiac ... Lysis #Syndrome #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
hydration - Hyperkalemia ... unless worrisome EKG ... with tetany or cardiac ... Syndrome #TLS #diagnosis ... #management #hematology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... octreotide), hyperK periodic ... reabsorption) Workup ... heparinized tube) • ECG ... #Treatment #potassium
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia If the patient is unconscious, signs of cardiac
CM5 continuous ECG ... abnormalities particularly potassium ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
Cardiac Tamponade ... • Diagnostic ... thoracotomy is a better treatment ... Intraoperative #Checklist ... #Workup
Cardiac Arrest - Guidelines for Crises in Anaesthesia The probable cause is one or more of: something
• Check ECG rhythm ... Hypovolaemia Hypo/hyperkalaemia ... CardiacArrest #Checklist ... #Diagnosis #Management ... #Workup
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia • Unexplained hypotension • Unexplained bronchospasm (wheeze may be absent
trolley, anaphylaxis treatment ... require prolonged treatment ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Neuroprotection following Cardiac Arrest - Guidelines for Crises in Anaesthesia Outcome from cardiac arrest is determined by
Obtain 12-lead ECG ... immediate postarrest period ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia Unexplained increase in ETCO2 AND tachycardia AND increased
dantrolene and cardiac ... with dantrolene Hyperkalaemia ... Intraoperative #Checklist ... #Diagnosis #Management ... #Workup
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