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Petechiae / Purpura - Differential Algorithm by Pathophysiology

Dr. Zaven Sargsyan @sargsyanz

#Petechiae #Purpura #Differential #Algorithm #Pathophysiology #diagnosis
Petechiae / Purpura ... @sargsyanz #Petechiae ... #Purpura #Differential ... #Algorithm #Pathophysiology ... #diagnosis #dermatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Henoch Schonlein Purpura ... Non-Palpable Rash: - Purpura ... Autoimmune Vasculitis (lupus ... Algorithm #Causes #dermatology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... Pathophysiology: ... #Diagnosis #Dermatology ... #Rash #Petechiae ... #Purpura #Palpable
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
mucosal bleeding (Petechial ... or purpuric rash ... SJIA], systemic lupus ... #Diagnosis #Management ... #Hematology #Rheumatology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... - Budd Chiari Syndrome ... #Systemic #Lupus ... Complications #pathophysiology ... #signs #symptoms
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Skin Findings: • Petechiae ... , Palpable purpura ... sensation or pain: • Petechiae ... • Palpable purpura ... • Goodpasture syndrome
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... rash, Vasculitis, Purpura ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
disease Palpable purpura ... Henoch Schönlein purpura ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... Sarcoidosis #dermatology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
Dermatoses: Sweet Syndrome ... Coagulopathy: Purpura ... Thrombocytopenia (ie petechiae ... MINTC #Mnemonic #dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management