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diagnosis differential dermatology sle erythematosus management vasculitis classification hairloss hematology oncology activation arthropathies arthropathy autoimmune comparison cryoglobulinemia cryoglobulins dermatologic diffuse
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Autoimmune Vasculitis (lupus ... deficiency Work ... cryoglobulins • Skin ... #Petechiae #Rash
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... Photosensitivity, Alopecia ... • Immunologic Workup ... Evolution: Chronic disease
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Differential Diagnosis Algorithm ... • Loose anagen syndrome ... - Secondary to Skin ... Disease • ... #causes
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Demyelinating syndromes ... pain (20%) Renal disease ... symptoms #diagnosis #rheumatology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Capitis - Skin ... Disease: Discoid ... lupus erythematosus ... , Loose anagen syndrome ... Vitamin D levels Systemic
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Differential Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Lupus - with Systemic ... like “butterfly rash
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... and permanent alopecia ... Non-autoimmune rheumatologic ... • Nonscarring alopecia
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... months to years) Systemic ... Photosensitivity, Alopecia ... Evolution: Chronic disease ... comparison #table #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Findings: • Petechiae ... Maculopapular rash ... • Goodpasture syndrome ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... mucosal bleeding (Petechial ... or purpuric rash ... lupus erythematosus ... #Rheumatology
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