9 results
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Neoplastic / Hematologic ... • Malignancy Infectious ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome ... #Algorithm #causes
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... accumulation of clinical ... immune deficiency, Drugs ... , Unknown cause ... #management #treatment
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
and clinical associations ... Infections 2. ... Drugs 5. ... #rheumatology # ... comparison #table
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... - Cytotoxic drugs ... Anemia #oncology #hematology ... #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... SLE], AOSD) • Infection ... ) • Sepsis • Drug-induced ... #Syndrome #Diagnosis ... #Management #Hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
than 1500 and clinical ... eosinophilia Secondary Causes ... Allergic disorders - Drug ... hypersensitivity - Infection ... #hematology #differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Summary Causes ... - Toxins - Drugs ... Statins - ETOH - Infection ... Dermatomyositis Clinical ... #Management #causes
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
acute coronary syndrome ... the determined cause ... #algorithm #management ... cardiology #treatment #table ... #pharmacology