10 results
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
on the highest dose ... only use lower doses ... at the lowest dose ... #Pharmacology # ... #Endocrinology
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
maximum daily dose ... Generally, the initial dose ... phosphate levels and doses ... Hyperphosphatemia #Dose ... #Dosing #Pharmacology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
the Total Daily Dose ... (stage IV or V CKD ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Calculate total daily dose ... dose for renal ... Diabetes #Mellitus #DM2 ... #comparison #table ... #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... • Increases insulin-mediated ... oral agent • Does ... #Summary #DM2 # ... diabetes #endocrinology
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
increase in the dose ... an increase in dose ... ml/min per 1.73 m2 ... evidence-based pharmacologic ... #KDIGO #eGFR #Insulin
Insulin Calculations for Type 1 Diabetes 

Insulin-to-Carb Ratio (ICR) 500/TDD = #g of carbs covered by
calculations used in dosing ... dose, but will ... normal mealtime dose ... #Pharmacology # ... Endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
mg maintenance dose ... smaller starting dose ... the maintenance dose ... the maintenance dose ... #Endocrinology
Acute Pancreatitis - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Epigastric abdominal pain (90%, characteristically
consider pain-dose ... low-fat (as safe as CLD ... • Antibiotics ... cholecystectomy during ... HyperTrig: D10+insulin
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
NSAIDs, β-blockers, Antibiotics ... (DM, DKA, octreotide ... VBG (acidosis), CK ... Elimination (see Table ... Transient, repeat dose