10 results
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Metformin - First ... Line Treatment ... form and consider using ... Indications #Titration #Pharmacology ... #Diabetes #DM2
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... oral agent • Does ... #Pharmacology # ... Summary #DM2 #diabetes ... #endocrinology
Metformin: Biguanide
Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
medication for treatment ... of type 2 diabetes ... titrating the dose ... 2000 mg/day) and using ... #Pharmacology #
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... Inhibitors #Renal #Dosing ... #Pharmacology # ... Management #Diabetes ... #DM2 #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Adjust insulin dose ... #Mellitus #DM2 ... #Medications #pharmacology ... #comparison #table ... #endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
the Total Daily Dose ... : Weight-Based Dosing ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
increase in the dose ... initiation of treatment ... an increase in dose ... ml/min per 1.73 m2 ... evidence-based pharmacologic
Insulin Calculations for Type 1 Diabetes 

Insulin-to-Carb Ratio (ICR) 500/TDD = #g of carbs covered by
calculations used in dosing ... mealtime insulin dose ... normal mealtime dose ... #DM1 #Pharmacology ... #Endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
GLP-1 Agonist Dosing ... drug to remain stable ... #semaglutide #Diabetes ... #Pharmacology # ... Endocrinology
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
, 350 mg/m2, and ... ) and initiate treatment ... hypertension, diabetes ... every 3 months during ... cardiology #oncology #pharmacology