7 results
Pharmacology, Toxicity and Management of Second Generation Antipsychotic (SGA) Overdose #Diagnosis #Management #Toxicology #Psychiatry #SGA #SecondGenerationAntipsychotics
Pharmacology, Toxicity ... Antipsychotic (SGA) Overdose ... #Diagnosis #Management ... #Toxicology #Psychiatry ... SecondGenerationAntipsychotics #Overdose
Toxidromes Compared: Anticholinergic, Cholinergic, Opioid, Sympathomimetic, Sedative-Hypnotic

During your physical exam, look for evidence of some of
Sedative-Hypnotic During ... acute cholinergic toxicity ... Opioid toxicity ... #Diagnosis #Toxicology ... #Toxidromes #Comparison
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
at anytime if toxicity ... - Intermittent dosing ... Therapeutic #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Prochlorperazine • Opioids ... Prolonged #QTc #Toxicity ... #Toxicology #Pharmacology ... #Diagnosis #prolongation
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... Leucovorin dosing ... the most severe overdoses ... #Toxicity #Management ... #Pharmacology
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
Tramadol - Toxicology ... mix of SNRI and opioid ... #Tramadol #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
GRACE-2 Guidelines for Low-Risk, Recurrent Abdominal Pain in the ED

1) Should adult ED patients with low-risk,
may be performed during ... pain receive non-opioid ... and/or non-pharmacologic ... We suggest an opioid-minimizing ... Pain #Emergency #diagnosis