6 results
Utilization of Antibiotics as Antidotes

Valproic Acid Toxicity:
Carbapenems 

Amatoxin Mushrooms: 
Polymyxin B, Penicillin, Cyclosporine

Infographic by Mike O'Brien
@MikeEMPharmD

#Antibiotics
Utilization of Antibiotics ... as Antidotes ... Valproic Acid Toxicity ... #Antidotes #Toxicology ... #Pharmacology
Carbamazepine Toxicity

Carbamazepine (CBZ) is an antiepileptic drug commonly prescribed for seizure disorders, trigeminal neuralgia, neuropathic pain,
Carbamazepine Toxicity ... Carbamazepine #Toxicity ... #Toxicology #Diagnosis ... #SideEffects #Adverse ... #Pharmacology
Toxidromes Compared: Anticholinergic, Cholinergic, Opioid, Sympathomimetic, Sedative-Hypnotic

During your physical exam, look for evidence of some of
Sedative-Hypnotic During ... acute cholinergic toxicity ... Opioid toxicity ... #Diagnosis #Toxicology ... #Toxidromes #Comparison
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
at anytime if toxicity ... - Intermittent dosing ... Therapeutic #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... Leucovorin dosing ... Methotrexate #Leucovorin #Antidote ... #Toxicology #Toxicity ... #Management #Pharmacology
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Risperidone • Antibiotics ... Prolonged #QTc #Toxicity ... #Toxicology #Pharmacology ... #Diagnosis #prolongation