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chronic cll leukemia lymphocytic agglutinin antibody classification cold common cvid extravascular hemeonc hodgkins immunodeficiency immunology intravascular lymphoma mds myelodysplasia myelodysplastic
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Differential Diagnosis ... Table Warm AIHA ... #Hemolytic #Anemia ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia ... 1) DIAGNOSE AIHA ... #Hemolytic #Anemia ... #diagnosis #management ... #treatment #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... (AIHA) "Warm" ( ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... : Warm AIHA, Cold ... Urobilinogen #Hemolysis ... Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... intravascular hemolysis ... #hemolytic #anemia ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... chemotherapy for low-risk disease ... AIHA, PRCA) • Treatment ... #hematology #hemeonc ... #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... hemolytic anemia ... DDX - Other causes ... #immunology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... • Neutropenia, anemia ... • Warm AIHA ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood ... just beneath the skin ... Myeloproliferative Disease ... count with differential ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
disorders Hodgkin ... nodosum • Immune hemolytic ... number of sites of disease ... classification #hematology ... #oncology #management
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