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oncology cll lymphocytic thrombocytosis acquired causes gap globulin hemeonc mds myelodysplasia myelodysplastic nonpalpable palpable platelets protein proteingap purpura signs symptoms
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Myelogenous Leukemia ... • Celiac disease ... #Diagnosis #Algorithm ... #Causes #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
thrombocythemia), Autoimmune disease ... #Acquired #vonWillebrand ... #Syndrome #Diagnosis ... #Management #treatment ... #hematology #differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... , coagulation disorders ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... • Infections: Chronic ... #Diagnosis #Algorithm ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... in adults • Disorder ... chemotherapy for low-risk disease ... #oncology #hematology ... #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... #oncology #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
disease) Differential ... Recurrent and chronic ... #Syndrome #diagnosis ... #management #signs ... #symptoms #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Marrow Failure • Chronic ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gammopathy, and skin ... changes (POEMS syndrome ... Connective tissue disorders ... gastric tumors • Hematology ... #diagnosis #hematology
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