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oncology lymphocytic arterial basophilia common embolism erythematosus gap globulin hemeonc hodgkins hypogammaglobulinemia immunodeficiency lupus mds myelodysplasia myelodysplastic pathophysiology proteingap sle
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... : • Chronic myeloid ... leukemia (CML) ... Diagnosis #causes ... #hematology #basophils
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... -> Invade Skin: ... lymphoma #Leukemia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... microglobulin Treatment ... #Leukemia #diagnosis ... workup #oncology #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disorder with hypogammaglobulinemia ... DDX - Other causes ... syndrome • Burns • Protein-losing ... hypogammaglobulinemia #immunology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... in adults • Disorder ... lymphoma (Richter ... #hematology #hemeonc ... #diagnosis #management
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Diagnosis Framework ... Myeloproliferative disease ... Testosterone - Coumadin skin ... intravascular coagulation ... pathophysiology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gammopathy, and skin ... Connective tissue disorders ... gastric tumors • Hematology ... : Lymphoma, Leukemia ... #diagnosis #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Treatment • Early ... #diagnosis #classification ... #hematology #oncology ... #management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Disease Classification ... pancreatitis, protein-losing ... with Lupus: • Chronic ... and leukemia • ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Marrow Failure • Chronic ... Myeloproliferative Disease ... blood count with differential ... #hematology #oncology
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