73 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... pseudotumor 4 phenotypes ... IgG4 #Related #Disease ... #phenotypes #workup
Alzheimer's Disease - Summary
 • Epidemiology
 • Pathophysiology
 • Risk Factors
 • Presentation
 • Diagnosis
 •
Alzheimer's Disease ... Epidemiology • Pathophysiology ... Treatment • Clinical ... #Alzheimers #Disease ... #Summary #diagnosis
Signs of Graves disease: 
• Goiter 
• Periorbital edema 
• Non-pitting edema causing hyperpigmented plaques 
•
Signs of Graves disease ... ) #Graves #disease ... #Signs #Clinical ... #Photo #Diagnosis
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
Behcet's Syndrome - Diagnosis ... Diagnostic Criteria ... test Most Common Clinical ... arterial aneurysms) Phenotypes ... #Diagnosis #criteria
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Syndrome #PUBS #pathophysiology ... #clinical #photo ... #differential #diagnosis
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... in macrophages Diagnosis ... in GBA1 gene Clinical ... #Diagnosis #Signs
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... severity of the disease ... prevalence of RP-ILD Phenotype ... muscle weakness Phenotype ... #dermatology #diagnosis
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... Pathogenesis and Clinical ... GravesDisease #pathophysiology ... symptoms #signs #diagnosis
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... share the same pathophysiology ... Cardiovascular disease ... Overproduction #diagnosis ... endocrinology #pathophysiology
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Lymphocytic Leukemia Clinical ... of autoimmune disease ... mature cytotoxic phenotype ... disease but cells ... hemepath #pathology #diagnosis