18 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... dechallenge • Acute ... #Diagnosis #Algorithm ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Cirrhosis • Chronic ... Viral Hepatitis ... Hepatopathy • Acute ... Viral Hepatitis ... (>1000): • DILI
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... Viral Hepatitis ... #Chronic #Liver ... gastroenterology #management #diagnosis
Focused evaluation algorithm for acute liver injury

#Liver #Injury #Acute #Evaluation #Algorithm #Diagnosis #Hepatology
Focused evaluation ... algorithm for acute ... Acute #Evaluation ... #Algorithm #Diagnosis ... #Hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... #differential #Diagnosis ... gastroenterology #algorithm ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... • Iatrogenic: DILI ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #chemistry #diagnosis ... #differential #Hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... B - Diagnosis and ... Management Algorithm ... Chronic Hepatitis ... #Algorithm #Diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Diagnosis Hepatocellular ... , Acute biliary ... #Differential #Diagnosis ... #algorithm #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... > 20x normal - Acute ... 5-10x normal - Chronic ... #Injury #hepatology ... #differential #diagnosis