8 results
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Approach to Thrombotic ... hemoglobin/hemosiderin, Hepatic ... antiglobulin test, PT/aPTT ... hemosiderin • PT/aPTT ... Management #Algorithm #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Pre-analytical cause (e.g. heparin ... thrombin inhibitors, heparin ... • Reduced liver ... #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
DIC • Severe Liver ... - bleeding or thrombosis ... 100mg/dL) - Heparin ... INR < 2.3 - APTT ... treatment #management #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Early liver disease ... unfractionated heparin ... Reduced liver synthesis ... Causes #diagnosis #differential ... #hematology #coagulation
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... cases: INR/PT, aPTT ... (liver disease, ... #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential ... Syndrome, Ischemic Liver ... Hyperhomocysteinemia - Heparin-induced ... pathophysiology #hematology ... #differential #
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Acquired: • Heparin ... associated with thrombosis ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
Evaluation for Thrombotic ... performed PT, PTT ... WBC count and differential ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology