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diagnosis hepatology ascites causes disease transaminitis algorithm injury saag aflp albumin arthritis biliary calling chemistry cholangitis comparison consultation function gap
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... • NAFLD • Cirrhosis ... ) • Non-hepatic ... Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... or chronic hepatitis ... Disease, Fulminant Hepatic ... #Diagnosis #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... /acute hepatitis ... sarcoidosis) • Liver ... metastasis • Fatty liver ... #Hypertension #Differential
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Acute sickle cell hepatic ... onset RUQ pain, jaundice ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
Important findings: jaundice ... Gl History - Cirrhosis ... - Vitals - LFTs ... disease work up ... Calling #Referral #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... • Others #LFTs
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
hyperpigmentation • Jaundice ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... malignancies, Hepatic ... cholangitis #diagnosis #workup
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... replaced by non-hepatic ... : < 1 • Cirrhosis ... chemistry #diagnosis #differential ... #LFTs #RValue #
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Pruritus, Mild jaundice ... imaging: Hepatic ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential
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