11 results
diagnosis hepatology algorithm disease injury transaminitis aflp causes obstetrics pregnancy acute arthritis biliary chemistry cholangitis cirrhosis comparison fatty function hepatobiliary
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... ) • Non-hepatic ... #Differential # ... Diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... biliary obstruction, HELLP ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... #Injury #Differential
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Pruritus, Mild jaundice ... , no necrosis HELLP ... #obstetrics #hepatitis ... #comparison #differential ... diagnosis #icp #HELLP
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Acute sickle cell hepatic ... onset RUQ pain, jaundice ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... NAFLD, Autoimmune, HELLP ... #Diagnosis #hepatology ... Transaminitis #LFTs ... #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Pregnancy - AFLP, HELLP ... • Alcoholic hepatitis ... • Others #LFTs
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
(DIC, ascites, jaundice ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Preeclampsia, HELLP ... #Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... replaced by non-hepatic ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Injury: • Hepatic ... Venoocclusive disease • Hepatic ... • Pregnancy: HELLP ... #differential #
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
hyperpigmentation • Jaundice ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... malignancies, Hepatic ... cholangitis #diagnosis #workup
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