7 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Acute sickle cell hepatic ... onset RUQ pain, jaundice ... crisis Acute Hepatic ... Hepatobiliary #hepatology ... #hepatitis #differential
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Pruritus, Mild jaundice ... imaging: Hepatic ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
hyperpigmentation • Jaundice ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... malignancies, Hepatic ... cholangitis #diagnosis #workup
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... splenomegaly • Hepatic ... hepatomegaly, hepatitis ... Disease #diagnosis #management ... #treatment #rheumatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
(DIC, ascites, jaundice ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Liver #Pregnancy #hepatology ... obgyn #diagnosis #management
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
(1 joint): • Septic ... parvovirus, HIV, hepatitis ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
• HBV, HCV - Hepatic ... loss, nausea, jaundice ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential ... #Diagnosis #Management