Phenotypes differential table hematology workup rheumatology diagnosis testing systemic sle disease

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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology

Microangiopathies In Systemic ... Erythematosus #SLE ... #hematology #rheumatology ... #differential # ... diagnosis #causes

Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.

rheumatoid arthritis SLE ... LungDisease #CTILD #Diagnosis ... #Differential # ... Comparison #Table ... #Pulmonary #Rheumatology

ANA Patterns and Associated Rheumatic Diseases:
• Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease

Associated Rheumatic Diseases ... erythematosus (SLE ... connective tissue disease ... ANA #patterns #rheumatology ... #diagnosis #differential

Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations:
1. HLH
2. Still's disease
3. Systemic

Diagnostic Schema ... Still's disease ... Systemic histoplasmosis ... Hyperferritinemia #Algorithm #Differential ... #Diagnosis #Hematology

Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Diagnosis Algorithm ... (diverse genotypes ... ): SS, SC, SE, Sβ ... #workup #hematology ... #testing

I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M Malar Rash
D

SHARP - Lupus Diagnosis ... Arthritis R Renal Disease ... #IMDAMNSHARP #sle ... #systemic #lupus ... erythematosus #rheumatology

Seronegative Inflammatory Arthritis - Differential Diagnosis
• Seronegative Rheumatoid Arthritis
• Infectious Arthritis: Viral, Bacterial,

Inflammatory Arthritis - Differential ... Diagnosis • Seronegative ... Rheumatic Disease ... #arthritides #Differential ... #Diagnosis #rheumatology

Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
• Epidemiology: 10-180/100,000, Typically Age 20-40, F:M

Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... • Immunologic Workup ... Evolution: Chronic disease ... Management #Summary #rheumatology

Approach to Hypoproliferative Macrocytic Anemia

• 812, Folate Deficiency
• MDS+
• Hypothyroid
• Liver Disease

Hypothyroid • Liver Disease ... Macrocytic #Anemia #differential ... #diagnosis #algorithm ... #hematology #workup

Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
• Associated

Systemic Lupus Erythematosus ... /systemic sclerosis ... @AnnKumfer #Systemic ... #Summary #diagnosis ... #rheumatology #

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