30 results
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
Summary of dosing ... recommendations in renal ... #Diabetic #Medications ... #Pharmacology # ... Renal #Impairment
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
Metformin Current Renal ... #Metformin #Renal ... #Dosing #Dose # ... Pharmacology #Diabetes
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... Summary Vasopressors ... Phenylephrine ... • Higher doses cause ... 2 mcg/kg/min): renal
Insulin Dosing Basics - Initiating Insulin for T2DM and Converting Insulin Products 

Insulin dosing can be
Insulin Dosing Basics ... For type 2 diabetes ... insulin for type 2 diabetes ... run into patient cases ... #Prescribing #Pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Summary Mechanisms ... agent • Does not cause ... #Summary #DM2 # ... diabetes #endocrinology
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
L-lactate - produced during ... salicylate toxicity causes ... ketoacidosis Renal ... acids in advanced renal ... Ketoacidosis - diabetic
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... Summary Mechanisms ... not definitively cause ... #Summary #DM2 # ... diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Inhibitors - Normal and Renal ... Dosing Increase ... patients have renal ... #Dosing #Pharmacology ... #Management #Diabetes
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus ... Medication Guide Classes ... insulin in Type 1 Diabetes ... insulin dose for renal ... #Medications #pharmacology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... Summary Mechanisms ... not definitively cause ... #Summary #DM2 # ... diabetes #endocrinology