36 results
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
Summary of dosing ... recommendations in renal ... #Diabetic #Medications ... #Pharmacology # ... Renal #Impairment
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
Metformin Current Renal ... #Metformin #Renal ... #Dosing #Dose # ... Pharmacology #Diabetes
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Hypernatremia - Differential ... perspiration Renal ... diuresis • Central diabetes ... • Nephrogenic diabetes ... nephrology #sodium #high
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
High Anion Gap Metabolic ... Acidosis (HAGMA) - Differential ... L-lactate - produced during ... ketoacidosis Renal ... Ketoacidosis - diabetic
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
algorithm Decreased renal ... • Drugs • Diabetic ... Normal, Renin High ... hypoplasia Aldosterone high ... nephrology #potassium #differential
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Summary Mechanisms ... CV mortality in high ... • Euglycemic diabetic ... #Summary #DM2 #
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... Summary Vasopressors ... Phenylephrine ... 2 mcg/kg/min): renal ... #Summary #management
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Differentials? ... 0.8 Normal + High ... acetaminophen dosing ... Ketoacidosis (starvation, diabetic ... Interpretation #Diagnosis #Summary
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... phlebotomy High ... (Uncontrolled diabetes ... causes #potassium #high
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
cell disease - Renal ... transplant - SLE High ... Low Renin - Diabetes ... Algorithm #diagnosis #differential