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Status Epilepticus Pharmacotherapy Guide • Phenytoin and Fosphenytoin • Valproate Sodium • Levetiracetam • Lacosamide •
Status Epilepticus ... Pharmacotherapy Guide • Phenytoin ... theABofPharmaC #Status
ConSEPT and EcLiPSE – Levetiracetam versus Phenytoin for Status Epilepticus - Visual Abstract Don't Forget the Bubbles,
Levetiracetam versus Phenytoin ... for Status Epilepticus ... not superior to phenytoin ... for convulsive status ... #Status #Epilepticus
Status Epilepticus Continuous seizure activity > 5-10 min OR >= 2 seizures without full recovery First line
Status Epilepticus ... Second line • Phenytoin ... mg/kg IV (Phenytoin ... hr infusion #Status
Amiodarone Toxicity and Monitoring Tremor Ataxia Ocular neuritis Corneal Microdeposits Bradycardia Pulmonary fibrosis Hepatotoxicity Blue-gray skin
DDI: digoxin, statins ... , warfarin, phenytoin
Emergency Treatment Algorithm for Convulsive Status Epilepticus 1. ABCDEFG (ABC's and Don't Ever Forget the Glucose) 2. Airway:
for Convulsive Status ... Fosphenytoin or Phenytoin ... medications in status ... #Convulsive #Status
Management of Convulsive Status Epilepticus in children Stabilization Phase (Seizure 0-5 minutes): • Check and maintain ABC
of Convulsive Status ... ) Established Status ... minutes): • IV Phenytoin ... not on regular Phenytoin ... Refractory Status
Emergency Treatment Algorithm for Convulsive Status Epilepticus 1. ABCDEFG (ABC's and Don't Ever Forget the
for Convulsive Status ... Fosphenytoin or Phenytoin ... MEDICATION IN STATUS ... anesthetics #Status
MGH Status Epilepticus Treatment Protocol 1st line (seizures ongoing for 5-10 mins): - Lorazepam 4mg IV
MGH Status Epilepticus ... 150mg PE/min) or, Phenytoin ... 10mg PE/kg IV or Phenytoin ... mins) REFRACTORY STATUS ... 48hrs) #MGH #Status
Medications Used in the Abortive Treatment of Ongoing Seizure Activity in the Emergency Department INITIAL THERAPY -
monitor respiratory status ... monitor respiratory status ... monitor respiratory status ... TREATMENTS - Phenytoin ... monitor respiratory status
Management Algorithm for Status Epilepticus • Assess airway, breathing, and circulation • Pulse oximetry • Electrocardiogram • Finger stick (give
Algorithm for Status ... Second-line therapy: • Phenytoin
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