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management hemophagocytic lymphohistiocytosis oncology chronic classification clinical cll cop cryptogenic dermatology hemeonc hodgkins leukemia leukostasis lymphocytic lymphoma lysis organizing pneumonia
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... following: • Fever ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... • Clinical: fever ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Presentation • Common Signs ... Pathophysiology ... Fever b. ... Treatment Approach ... #Management #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - 80% have fever ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... classification #hematology
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
The signs and symptoms ... ) ▪ Malaise, fever ... Syphilis #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Physical Exam/Signs ... microglobulin Treatment ... #workup #oncology ... #hematology
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... Males=Females SIGNS ... Cough, dyspnea, fever ... identified (autoimmune, meds ... , neoplastic) TREATMENT
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