28 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
thickening Signs ... calcinosis • Pulmonary ... disease), PAH (pulmonary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
rubbing of the skin ... syndrome, caused ... differentiating between the diagnosis ... #Dermatology #PhysicalExam ... Clinical #SJS #skin
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... Disorientation, vertigo Diagnostic ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Kussmaul's sign in Constrictive Pericarditis 

A 50-year-old woman with a remote history of mediastinal lymphoma (age
on her chest (photo ... the underlying diagnosis ... Causes = RV failure ... pericarditis (this case ... #PhysicalExam #
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... organ-specific signs ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Lung Findings on Physical Exam
Crackles:
 • Short, discontinuous, sounds mostly heard during inspiration
 • Caused by
inspiration • Caused ... alveoli as seen in pulmonary ... Lung #Findings #Pulmonary ... #PhysicalExam # ... diagnosis #signs
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
Infarction and Pulmonary ... associated with rheumatologic ... life-threatening causes ... Pericarditis #Symptoms #Signs ... #Diagnosis
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
manifestations Skin ... inflammation tends to cause ... interstitial lung disease/pulmonary ... pathophysiology #signs ... #symptoms #diagnosis
Kussmaul's Sign and Friedreich's Sign on Neck Examination

A middle-aged M with unknown PMH presents with dyspnea.
Kussmaul's Sign ... Most likely diagnosis ... blue-colored spot on the skin ... the underlying cause ... Friedreichs #Neck #JVP #PhysicalExam
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
thrombophlebitis, pulmonary ... Cryofibrinogenemia Diagnosis ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis ... #rheumatology #