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diagnosis differential rheumatology signs management dermatology clinical pathophysiology vasculitis hematology causes oncology pain rash algorithm neurology syphilis infections infectiousdiseases joint
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... response to local skin ... meningitis), MCC CNS symptoms ... inhibitors • Uveitis- Ophthalmology ... management #signs #symptoms
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... • Felty's syndrome ... Shrinking lung syndrome ... Scleroderma Thickened skin ... , Marfan syndrome
Highlighted Conditions With Arteritis or Periarteritis of the Coronaries Takayasu's arteritis: - Onset < 40 yrs -
yrs - Cranial symptoms ... Polyarteritis nodosa: - Skin ... Ulceration GI tract - Ocular ... IgG4-related disease ... Erdheim-Chester disease
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Behcet's Syndrome ... Criteria for Behget's Syndrome ... vasculitis - Skin ... Wide variety of skin ... vasculitis) • Arthritis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
, and ocular inflammation ... ulcers, cutaneous, ocular ... • Cogan Syndrome ... : - Ocular inflammatory ... Presentation - Systemic Symptoms
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- (Reiter’s syndrome ... • Psoriatic arthritis ... - with the skin ... Inflammatory Bowel Disease ... should have other symptoms
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
IgM deposits • Nodular ... : • Temporal arteritis ... • Takayasu's arteritis ... Vasculitis: • Behcet Disease ... • Cogan syndrome
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... • Progressive symptoms ... , and ocular inflammation ... ulcers, cutaneous, ocular ... : Ocular inflammatory
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
infection • Lyme disease ... migrans • Lyme disease ... • Gonococcal arthritis ... Antiphospholipid-antibody syndrome ... • Psoriatic arthritis
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... Arthritis: • Colchicine ... Skin manifestations ... refractory lesions Ocular ... #Syndrome #Treatment
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