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diagnosis management signs comparison differential erythematosus systemic ana antibodies antinuclear arteritis behcet classification cold disease druginduced gca giantcell patterns polychondritis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... lesions Abdominal pain ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... constitutional symptoms ... 40, F:M 9:1 • Clinical ... #table #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... context of other symptoms ... likely it will be clinically ... erythematosus (SLE ... ANA #patterns #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... 3rd Decade Skin ... Arthritis: • Joint pain ... : • Symptoms limited
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral aphthae : SLE ... • Arthritis: SLE ... inhibitors • Uveitis- Ophthalmology ... Nonsurgical abdominal pain ... #rheumatology #
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
life Causes and clinical ... and duration of symptoms ... Nausea, abdominal pain ... Urticaria #diagnosis #rheumatology ... #comparison #table
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
renal failure Clinical ... Self-limiting, chronic but stable ... , cough, chest pain ... nodes: 13-15%, skin ... (16-32%): lupus
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... claudication: pain ... required due to skip ... them, but urgent rheumatology ... required +/- prompt ophthalmology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... Sudden onset of pain ... • Inner ear • Skin ... cases such as: • SLE ... Polychondritis #rheumatology
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