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diagnosis hematology oncology vasculitis allergy arthropathies arthropathy behcet causes chronic classification cll disease disorders eosinophilia erythematosus joint lupus lymphocytic management
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Leukemia, Tumour ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Hematology #Oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behcet disease) Differential ... Oral aphthae : SLE ... tears, Ischemia, Leukemia ... inhibitors • Uveitis- Ophthalmology ... #rheumatology #
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Eosinophilia - Differential ... Diagnosis Algorithm ... • Eosinophilic Leukemia ... GI, lung, skin), ... , Sarcoidosis, SLE
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Hepatomegaly • Skin ... • Richter’s Syndrome ... • Sezary syndrome
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... Hodgkin lymphoma and leukemia
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... just beneath the skin ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... blood count with differential
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... Presentation: Systemic Symptoms ... • Progressive symptoms ... #Diagnosis #Rheumatology
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