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hematology leukemia mds myelodysplastic treatment anemia aplastic apml chronic cll differential differentiation eosinophilia eosinophils hes hypereosinophilia hypereosinophilic lymphocytic monoclonal multiple
Multiple Myeloma - Treatment Algorithm a) Newly Diagnosed Myeloma: Transplant Eligible b) Newly Diagnosed Myeloma: Transplant Ineligible doi: 10.1038/s41408-020-00359-2 #Multiple
Myeloma - Treatment Algorithm ... a) Newly Diagnosed ... Eligible b) Newly Diagnosed ... #management #hematology ... #oncology
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... Myelodysplastic #Syndrome ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Headaches • Pale skin ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lower-extremity joints Diagnosis ... • A clinical diagnosis ... #Rheumatology # ... diagnosis #management ... #Dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... just beneath the skin ... #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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