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hematology causes algorithm dermatology anemia hemolytic nonpalpable palpable platelet table ttp blastomycosis bruising clinical defects evaluation extravascular hemolysis hemolyticuremicsyndrome hus
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... of thrombocytopenia ... purpura/hemolytic ... 2012, p 193 #Diagnosis ... #Differential #
Causes of Purpura - Differential Diagnosis Disruption in Vascular Integrity: • Trauma, Infection, Vasculitis, Drug induced
- Differential ... Diagnosis Disruption ... collagen vascular disorders ... Primary hemostasis: Thrombocytopenia ... #Diagnosis #vasculitis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... inflammation • Thrombocytopenia ... #Differential # ... Diagnosis #hematology
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... Microangiopathy #thrombocytopenic ... #purpura #TTP # ... HemolyticUremicSyndrome #HUS #thrombocytopenia ... #Comparison #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... Diagnosis and Workup ... #Differential # ... Diagnosis #Causes ... #Workup #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... Congenital - Rare disorders ... bypass Vascular disorders ... peds #pediatrics #diagnosis ... #differential #
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... hemostasis: - Thrombocytopenia ... Vasculitis - Collagen disorders ... deficiency Work
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... lymphoproliferative disorders ... Extravascular #Causes #differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #workup #hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... MYH9-Related Disorder ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology
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