15 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... #Systemic #Lupus ... Summary #diagnosis #rheumatology ... #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Erythematosus #SLE ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... erythematosus [SLE ... #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Erythematous, macular ... Non-autoimmune rheumatologic ... vein thrombosis Hematologic ... Erythematosus #Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Oral aphthae : SLE ... • Arthritis: SLE ... Reactive Arthritis, AS ... #diagnosis #management ... signs #symptoms #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... refractory lesions Ocular ... case) • Surgery may ... #Treatment #management ... #pharmacology #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
myopathy • Anti MAG ... Hypergammaglobulinemic macular ... to cold IgG • Lupus ... vascular beds-renal, retinal ... Paraproteinemias #Hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
pulmonary emboli, and ocular ... thrombi including retinal ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... • Cogan Syndrome ... systemic lupus ... vasculitis, and SLE ... differential #diagnosis #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... the collar bone ... #Rheumatology # ... diagnosis #management ... #Dermatology