6 results
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Indications for Albumin ... for Management ... of Cirrhosis • ... #Cirrhosis #treatment ... #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Phosphatase and Bilirubin ... circulates with albumin ... Released from albumin ... Laboratory #Metabolism #ASTALT ... #Hepatology #Pathophysiology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
week • Direct bilirubin ... Production: • Albumin ... normal AST/ALT AST ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
or fibrosis • Cirrhosis ... injury (INR > 2, bilirubin ... mg/dL) or acute liver ... #Indications #management ... #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
thrombocytopenia • Liver ... ↑ AST ↑ ALT ↑ bilirubin ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology