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management anemia oncology pathology causes classification hemolytic treatment workup agglutinin aplastic approach chronic cll coagulation cold comparison dic differential disease
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
Pity this Giant ... from an elderly pt ... Parvovirus #Pathology #Smear ... #Microscopy #Hematology ... #Clinical
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Normochromic RBCs on Smear ... Deficiency • Aplastic ... #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... /PTT • Low plasma ... /INR: ↑ • PTT: ... • Peripheral smear ... treatment #management #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... and laboratory diagnosis ... hemolytic #anemia #Hematology ... #Microscopy
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
occurs when the plasma ... #Clinical #Pathology ... #Blood #Smear # ... Microscopy #Rouleaux ... #Formation #Hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... , PTT, and fibrinogen ... of Peripheral blood ... smear - Shows schistocytes ... #Workup #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... ↑ PTT • ↑ Fibrin ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... Phagocytosis of blood ... accumulation of clinical ... Cytopenia +++ (Plt ... treatment #summary #rheumatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
illness, high plasma ... of high parity blood ... sequestration and activation ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... Immunoglobulin M (IgM) • Blood ... smear - RBC agglutination ... sensitize red blood ... hemolytic #anemia #hematology
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