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Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
malignancy Pathophysiology ... - GH-secreting pituitary ... (Up to 30% of pituitary ... • Pituitary ... Endocrinology #Treatment #Pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... endocrinology #pathophysiology ... #pituitary
Acromegaly Caused by over-secretion of growth hormone (GH) from the pituitary gland. The condition is rare
Acromegaly Caused ... (GH) from the pituitary ... #Acromegaly #Signs
Hypothalamic releasing hormones and the pituitary trophic hormones. #Hypothalamic #Pituitary #Hormones #Release #Trophic #Anterior #Hypothalamus #Endocrinology
hormones and the pituitary ... #Hypothalamic #Pituitary ... Endocrinology #Pathophysiology
Multiple Endocrine Neoplasias (MEN syndromes) MEN I • Hyperparathyroidism • Hypercalcemia • Possible ZE syndrome • Various
syndrome • Various Pituitary ... path • Acromegaly
Clinical Effects of Large and Small Pituitary Tumours Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
Large and Small Pituitary ... infarction/expansion (pituitary ... Hypogonadism • Acromegaly ... and polyuria #Pituitary
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... plate fusion -> acromegaly ... rare causes of acromegaly ... endocrinology #pathophysiology
The principal endocrine 'axes' and glands. Parathyroid glands, adrenal zona glomerulosa and endocrine pancreas are not
controlled by the pituitary ... Endocrinology #Pathophysiology ... Pathways #Diagnosis #Pituitary
Acromegaly in patient with a pituitary adenoma #acromegaly #pituitary #adenoma #GnRH #Hand #PhysicalExam #clinical #photo
Acromegaly in patient ... with a pituitary ... adenoma #acromegaly ... #pituitary #adenoma
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... Symptomatic pituitary ... • For pituitary ... mnemonic #GLFTAP #pathophysiology
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