12 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
, difficult to diagnose ... malignant) to diagnose ... salmon-colored maculopapular ... BrighamChiefs #AdultOnset ... #management #treatment
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
Maculopapular Rashes ... differential diagnosis ... drug reaction or pityriasis ... broader differential diagnosis ... #Diagnosis #Dermatology
Central Distribution, Febrile / Ill:
 - Viral Exanthem 
 - Lyme Disease (erythema migrans) 
Central Distribution,
Reaction - Pityriasis ... twitter.com/BirksMD #Maculopapular ... Rash #Algorithm #Diagnosis
Tinea Versicolor (Pityriasis versicolor) 
NOT a dermatophyte infection 
Caused by saprophytic, lipid-dependent yeasts 
Clinical 
 •
Tinea Versicolor (Pityriasis ... erythematous Diagnosis ... meatballs appearance Management ... Dermatology #SkinRash #Diagnosis ... #Management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... Prunelle Getten #AdultOnset ... Stills #Disease #diagnosis ... #management #treatment
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
• Leukocytosis Diagnosis ... widely used for diagnosis ... nonpruritic macular or maculopapular ... Stills #disease #AOSD ... #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Maculopapular ... Criteria for Diagnosis ... Exanthematous Pustulosis Management ... #dermatology #diagnosis ... #management
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
Typical skin rash: maculopapular ... polyarteritis nodosa #AdultOnset ... Yamaguchi #Criteria #Diagnosis
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Differential Diagnosis ... Paradoxical emboli via ASD ... Endocarditis Diagnosis ... #Endocarditis #diagnosis ... #management #cardiology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
/sx urticaria, maculopapular ... #Transfusion #diagnosis ... #management #hematology