12 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... salmon-colored maculopapular ... BrighamChiefs #AdultOnset ... #Stills #Disease ... #diagnosis #management
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
Maculopapular Rashes ... APPROACH The term maculopapule ... Maculopapular rashes ... assessed for Lyme disease ... drug reaction or pityriasis
Central Distribution, Febrile / Ill:
 - Viral Exanthem 
 - Lyme Disease (erythema migrans) 
Central Distribution,
Exanthem - Lyme Disease ... Reaction - Pityriasis ... Syphilis - Lyme Disease ... twitter.com/BirksMD #Maculopapular
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... autoinflammatory diseases ... Prunelle Getten #AdultOnset ... #Stills #Disease ... #diagnosis #management
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Onset Still's Disease ... nonpruritic macular or maculopapular ... onset #Stills #disease ... #AOSD #diagnosis ... #rheumatology #management
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
Onset Still's Disease ... Typical skin rash: maculopapular ... - Inflammatory disease ... polyarteritis nodosa #AdultOnset ... #Stills #Disease
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Maculopapular ... Exanthematous Pustulosis Management ... withdrawal • Mild disease ... treatment • Severe disease ... dermatology #diagnosis #management
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
rash (not hives), Maculopapular ... If infectious disease ... and Infectious Disease ... Prescription #algorithm #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... Adult-onset Still disease ... of underlying disease ... erythematosus [SLE], AOSD ... Syndrome #Diagnosis #Management
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Pre-existing valvular disease ... Congenital heart disease ... Paradoxical emboli via ASD ... • Metastatic disease ... Endocarditis #diagnosis #management