24 results
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... spontaneously (before any treatments ... leukemia (both ALL ... malignancies Treatments ... #Tumor #Lysis #Syndrome
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... hyperleukocytosis (AML ... Hyperviscosity #Syndrome ... Differential #Diagnosis #Treatment
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... Antiphospholipid antibodies (aPL ... Anticardiolipin antibodies (aCL ... to be present Treatment ... Antiphospholipid #Syndrome
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... have fever - ACS ... organ damage • Treatment ... Low calcium • Treatment ... - Hyperkalemia treatment
Management of Serotonin Syndrome
Identify and stop all serotoninergic medications
 • Avoid inadvertent Rx of serotoninergic meds
Management of Serotonin Syndrome ... Identify and stop all ... ucsdim #Serotonin #Syndrome ... #Management #treatment
REBEL Review 99: Serotonin Syndrome via Yosuf Alam, MSIV

Presentation: Altered mentd status, Seizures, Myoclonus, Hypertension, Hyperthermia
99: Serotonin Syndrome ... Cornerstone of treatment ... discontinuing all
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... factor (GCSF) treatments ... marrow studies Treatment ... progression to AML ... Immunosuppressive treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... complete paralysis of all ... Miller Fisher Syndrome ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... Renal Failure Treatment ... Differentiation #Syndrome
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Encephalopathy Syndrome ... Clinico-Radiological Syndrome ... circulation: MCA ACA ... epilepticus Treatment ... underlying cause • Treatment