21 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Exogenous (KCL ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology ... #potassium #medications
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... and sodium • Dosing ... binds magnesium • Dosing ... and calcium • Dosing ... #medications #pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... • NSAIDs • ACE ... Medications 2. ... potassium #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Clenching of fist during ... • NSAIDs • ACE ... Medications 2. ... potassium #high #nephrology
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
restricted due to hypercalcemia ... Only* #CKD #Nephrology ... Hyperphosphatemia #Dose #Dosing ... #Pharmacology #
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
: Treatment of Hyperkalemia ... oral suspension DOSING ... who have chronic hyperkalemia ... ACE inhibitors, ... #Pharmacology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
recessive salt-losing ... distal tubule. ↑ Nacl ... H+ secretion → Hypokalemia ... Pathophysiology #nephrology
Intern Pocket Cards - Inpatient Blood Pressure Management Guide
ß-blockers:
 • Metoprolol, Carvedilol, Labetalol
 • Bradycardia, heart
exacerbation ACEl ... Valsartan • AKI, hyperkalemia ... BloodPressure #medications ... #Inpatient #pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... STOP offending medications ... Ca-gluconate or 1g CaCl ... Treatment #potassium #nephrology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
Post-operative phenomenon, Medications ... restriction • All ... if you plan on using ... Start with lg NaCl ... #hyponatremia #nephrology