14 results
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Diagnosis Algorithm ... Transcellular Shift: • Alkalosis ... • Refeeding syndrome ... vomiting) • Low ... #Algorithm #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... Pathophysiology #nephrology ... #diagnosis
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
consumption • Low ... - Metabolic Alkalosis ... #diagnosis #Algorithm ... differential #potassium #nephrology ... #low
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... • Normal or low ... Hypochloremic metabolic alkalosis ... #diagnosis #nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
ON (UNa < 30): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... Primary polydipsia, Low ... Hyponatremia #Algorithm #diagnosis ... #sodium #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
• Normal/low ... , Gitelman syndrome ... the excretion of sodium ... urine #Algorithm #nephrology ... #differential #diagnosis
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Present (Uosm ≥100): Hypovolemia ... Cirrhosis, Nephrotic syndrome ... #differential #diagnosis ... #table #sodium ... #nephrology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
polyneuropathy (e.g ... Guillain-Barré syndrome ... Hyperreflexia: • Hypocalcemia ... #differential #diagnosis ... #table #neurology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... • Euvolemic (Low ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... test (only if no clear ... Elimination (see Table ... acidosis) • Low ... Treatment #potassium #nephrology