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management differential pulmonary cardiology hematology neurology signs abscess amiodarone apml barre bulimianervosa causes complexes complications congenital differentiation encephalopathy gbs guillain
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... unless worrisome EKG ... #TLS #diagnosis
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Abscess Pathophysiology ... shows a small, stable ... residual lesion or is clear ... • Vasculitis (e.g
Congenital Long QT Syndrome: Illness Script Who? - Kids or young adults, usually < 30 - high
QT Syndrome: Illness ... live births Symptoms ... **Get baseline EKG ... family history) Treatment ... #Diagnosis #Cardiology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... granulomas within the lungs ... (e.g. incidental ... Self-limiting, chronic but stable
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Prednisone 5mg/kg ... : >3 symptoms, or
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... • EEG: With persistent ... epilepticus Treatment ... underlying cause • Treatment
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
(e.g., long QT ... syndrome, ARVC) ... Digoxin toxicity Symptoms ... 300 = NSVT EKG ... more intensive treatment
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... recent DAN) • EMG ... or serologies + symptoms ... sparing of the lung ... #management #treatment
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... respiratory distress syndrome ... gradually with symptoms ... Improvement in symptoms ... macrophages Treatment
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... the underlying pathophysiology ... and cauda equina TREATMENT ... Guillain #Barre #Syndrome
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