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management signs hematology neurology abscess apml barre bulimianervosa causes complications differential differentiation encephalopathy gbs guillain leukostasis lung lysis oncology posterior
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... unless worrisome EKG ... #TLS #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Prednisone 5mg/kg ... : >3 symptoms, or
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... antibiotics once stable ... shows a small, stable ... residual lesion or is clear ... • Vasculitis (e.g
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... at the time of diagnosis ... (e.g. incidental ... Self-limiting, chronic but stable
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... • EEG: With persistent ... epilepticus Treatment ... underlying cause • Treatment
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... the underlying pathophysiology ... and cauda equina TREATMENT ... Guillain #Barre #Syndrome
Serotonin Syndrome: Pathogenesis and Clinical Findings Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
drugs of abuse (e.g ... make a clinical diagnosis ... #Pathophysiology ... #Psychiatry #Diagnosis ... #Signs #Symptoms
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
• Boerhaave syndrome ... of nutrients (e.g ... Complications #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
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