5 results
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Diseases Nephrotic ... Deposition of matrix ... • Breaks in GBM ... #spectrum #diagnosis ... #nephrology #nephritic
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... (Dense deposit disease ... immune deposits on EM ... glomerulopathy, radiation nephritis ... #nephrology #diagnosis
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Electron Microscopy (EM ... • Anti-GBM disease ... #diseases #nephrology ... #pathology #comparison ... #table #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
disease (hematuria ... nephropathy, lupus nephritis ... staining on IF • No EM ... #Differential #Diagnosis ... #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... atypical HUS; MPGN ... cluster, the diseases ... #nephrotic #syndrome ... #nephrology