10 results
Hypophosphatemia Diagnostic Algorithm
- GI Losses
- Redistribution
- 1° HPT
- 1° Renal PO4 wasting: Hereditary, TIO, Fanconi Syndrome,
, TIO, Fanconi Syndrome ... Hypophosphatemia #phosphorus ... #low #diagnosis ... #Algorithm #differential ... #nephrology
Workup for Hypophosphatemia - Differential Diagnosis Framework
Rule out spurious hypophosphatemia: paraproteinemia, acute leukemia
Measure Urine Fractional Excretion
Hypophosphatemia - Differential ... absorption (Antacids, Phosphorus ... • Normal or Low ... - Normal or Low ... Workup #phosphate #nephrology
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Hypophosphatemia - Differential ... Appropriately Low ... Hypophosphatemia #Differential ... Diagnosis #Algorithm #nephrology ... #phosphorus #workup
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cell epithelial sodium ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
can be high or low ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #differential ... #diagnosis #table ... #sodium #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypernatremia - Differential ... • Euvolemic (Low ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
metastasis (hungry bone syndrome ... Potassium depletion, Phosphorus ... Hypomagnesemia #Causes #differential ... #diagnosis #nephrology ... #magnesium #low
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
alkalosis • Normal/low ... , Gitelman syndrome ... the excretion of sodium ... urine #Algorithm #nephrology ... #differential #
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... Cirrhosis, Nephrotic Syndrome ... #Hyponatremia #Differential ... diagnosis #causes #nephrology ... #sodium #low
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... alkalosis • Normal or low ... ratio 0.5%) Differential ... #diagnosis #nephrology