83 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Initial screening test ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #SLE #Summary #diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Immune Complex: Systemic ... Rheumatoid arthritis, Systemic ... , biopsy By Tess ... #differential #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... association • M > F Clinical ... (Clinical Dx). ... is a skin prick test ... inhibitors • Uveitis- Ophthalmology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... • Homogeneous: Systemic ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #rheumatology #diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... Liver Function Tests ... Cholestatic liver disease ... Myelodisplastic syndrome ... Psychiatric Disease
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Clinical Presentation ... Fever is the main clinical ... Liver function tests ... #Diagnosis #Management
Horner's Syndrome: Loss of sympathetic nervous system input to (in this case) right eye. 
Note that
Horner's Syndrome ... sympathetic nervous system ... #Ophthalmology ... #Photo #Horners ... #Syndrome #Ptosis
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
central nervous system ... and less common diseases ... important, as early diagnosis ... infections • Lyme disease ... MRI lesions and clinical
Pupillary Abnormalities  Overview
 - Unequal Pupils (anisocoria)
 - Tonic pupil (Adie's pupil)
 - OculomotorNerve (CN
- Homer's Syndrome ... central nervous system ... #Diagnosis #Ophthalmology ... GrepMed Recommended Text
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Demyelinating syndromes ... pain (20%) Renal disease ... signs #symptoms #diagnosis