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differential monoclonal anemia acute agglutinin aki aplastic cancer classification clinical cold disease gammopathies gammopathy gap globulin hemolytic injury kidney leukemia
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... - Differential Diagnosis ... Neurologic-Centered ... capillary leak syndrome ... #hematology #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• MM • WM • MGUS ... et diutinum Neurologic ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
significance (MGRS ... change disease • Hematologic ... #AKI #Cancer #Oncology ... #Differential #Diagnosis ... Classification #Nephrology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
plasmacytoma, POEMs syndrome ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... - Mycoplasma, EBV ... significance (MGUS ... hemolytic #anemia #hematology ... #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• Cytopenia -> BM ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... affects the skin, neurologic ... cognitive impairment, neurologic ... pain and GN Anti-GBM ... #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Gammopathy Include: • MGUS ... changes (POEMS syndrome ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
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