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differential algorithm clinical neurology causes cns glomerular comparison diseases electronmicroscopy fibrocellular hemepath infections nephrotic ophthalmology proteinuria sem syndrome aids biopsy
Kidney Biopsy - Diagnosis Algorithms 1) Normal Glomerulus by LM 2) Glomerular Crescents 3) Double Contours of GBM 4) Endocapillary
Kidney Biopsy - Diagnosis ... 2) Glomerular Crescents ... Double Contours of GBM ... #Algorithm #nephrology ... #pathology
Spectrum of Glomerular Diseases Nephrotic - Mechanism: • Injury to podocytes • Changed architecture: Scanning. Deposition of
• Breaks in GBM ... • Crescent formation ... differential #spectrum #diagnosis ... #nephrology #nephritic
This image shows acellular scanning EM with a fibrocellular crescent with entrapped RBCs. The glomerulus is
acellular scanning EM ... fibrocellular crescent ... fibrocellular #crescent ... SEM #clinical #nephrology ... #pathology
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 Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
proteinuria) - Crescent ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... #Differential #Diagnosis ... #Nephrology
Guide to systemic mastocytosis Criteria for diagnosis: at least 1 major and 1 minor or 3 minor
Criteria for diagnosis ... minor criteria present ... unless an AHN is present ... mastocytosis #hemepath #pathology ... #algorithm #diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... 150mg/d protein present ... proliferative • Anti-GBM ... #Proteinuria #Nephrology ... #Differential #Diagnosis
This image shows acellular scanning EM with empty lacunar spaces of a fibrocellular crescent previously occupied
acellular scanning EM ... fibrocellular crescent ... fibrocellular #crescent ... SEM #clinical #nephrology ... #pathology
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 CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Chorioretinitis • Diagnosis ... granulomatosis: • EBV-associated ... disease • 30% present ... #differential #diagnosis ... causes #radiology #neurology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
the differential diagnosis ... Cytomegalovirus; GBM ... or may not be present ... Hematuria may be present ... nephrotic #syndrome #nephrology
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia Clinical - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
disease - Most present ... presentation (PB, BM ... Leukemia #hemepath #pathology ... #diagnosis
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