30 results
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... similar aggregation pattern ... agonists • This pattern ... considered first-line testing ... #disorders #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Disorders - Differential ... smear, HIV/HCV testing ... or if a primary hematologic ... #Disorders #Differential ... Causes #Workup #hematology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... without platelet ... MYH9-Related Disorder ... comparison #table #differential ... #diagnosis #hematology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia - Differential ... Connective tissue disorders ... Thrombocytopenia #Differential ... Diagnosis #Algorithm #hematology ... #platelets
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... RBC's secondary to platelet ... Thrombocytopenia • Platelet ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Sequestration Disordered ... Platelet Function ... Connective Tissue Disorders ... Algorithm #Causes #Hematology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... Nuclear Patterns ... Antinuclear #Antibody #Testing ... #differential # ... diagnosis #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... #Eosinophil #Disorders ... #Algorithm #Differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... with or without platelet ... Consider RBC membrane disorder ... Algorithm #workup #hematology ... #testing
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
PLATELETS Mnemonic ... Thrombocytopenia P - Platelet ... Disorders (DIC, ... Thrombocytopenia #Differential ... #Diagnosis #Hematology