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2021 ACR/VF Guidelines for Management of Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA)

#Granulomatosis #Polyangiitis #GPA
Polyangiitis (GPA ... Polyangiitis (MPA ... #Polyangiitis #GPA ... #rheumatology #algorithm ... #vasculitis
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management
 • Giant Cell Arteritis (GCA)
 •
Polyangiitis (GPA ... ), Microscopic Polyangiitis ... (MPA) • Eosinophilic ... Polyangiitis (EGPA ... ACR2021 #Guidelines #algorithm
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
ANCA (C-ANCA): GPA ... >>> MPA > eGPA ... ): eGPA, MPA >>> ... GPA Stanford Internal ... Glomerulonephritis #Vasculitis
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (GPA ... ), microscopic polyangiitis ... (MPA), and eosinophilic ... polyangiitis (EGPA ... Microscopic polyangiitis
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (GPA ... Polyangiitis (MPA ... - ACR/VF 2021 Guidelines ... #Polyangiitis #GPA ... #MPA #ANCA #Vasculitis
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... inflammation: • Microscopic ... polyangiitis (GPA ... polyangiitis (eGPA ... differential #diagnosis #algorithm
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Vasculitis Involving ... • ANCA Associated ... : - Microscopic ... polyangiitis - EGPA ... - GPA Cutaneous
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... capillaritis • EGPA ... > PR3 60% • GPA ... • ANCA (Dx: GPA ... , EGPA, microscopic
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... polyangiitis (GPA ... GPA causes disease ... polyangiitis • EGPA ... #Polyangiitis #GPA
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Infection - Vasculitis ... - Autoimmune Vasculitis ... RA, Sjogren's, GPA ... , EGPA, Microscopic