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diagnosis algorithm metabolic alkalosis causes hypokalemia syndrome management neurology potassium urinary urine acidosis aniongap comatose defects encephalopathy epithelial hypochloremia inherited
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... thiazide-sensitive sodium-chloride ... distal tubule. ↑ Nacl ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
Algorithm Cl- ... Kidney loss of Cl ... Bartter syndrome, Gitelman ... urine #Algorithm #nephrology ... #differential #
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Hypochloremia - Differential ... - Bartter - Gitelman ... • Fatigue Chloride ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
Metabolic Alkalosis - Differential ... Algorithm - Urinary Chloride ... suction, Congenital chloride ... Bartter syndrome, Gitelman ... Metabolic #Alkalosis #Differential
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential ... Hypertensive: • High Al ... Bartter's syndrome, Gitelman's ... #Hypokalemia #Differential ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... • High Urine Cl ... Bartter Syndrome, Gitelman ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium chloride ... ratio 0.5%) Differential ... • Congenital chloride ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... • High Urine Cl ... Bartter Syndrome, Gitelman ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #Nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis ECF volume contracted: urine chloride concentration <20 meq/L • Gastric alkalosis:
Metabolic Alkalosis: Differential ... contracted: urine chloride ... furosemide-like lesion) • Gitelman ... Metabolic #Alkalosis #Differential ... Diagnosis #Causes #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
syndrome - Na-K-2Cl ... barrtin (recruits Cl ... ascending limb Gitelman ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
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