11 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... have fever - ACS ... , AKI, acute limb ... Lysis Syndrome: • Pathophysiology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Less Typical Symptoms ... (Sens. 81% for acute ... effusions). 1/5 pts w/ acute ... : • ACE Inhibitors
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle ... lights are a key symptom ... bodies, shallow ACD ... Photophobia #Acute ... ClosedAngle #Glaucoma #pathophysiology
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Chlorpromazine ACh ... Block action of ACh ... Extrapyramidal Symptoms ... bradykinesia/akinesia • Acute ... #SideEffects #pharmacology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... • Rare: DAH, acute ... Diagnosis: >3 symptoms ... , Anaphylaxis, Acute
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
pituitary masses of all ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... : Acute onset 2 ... circulation: MCA ACA ... syndrome, ADEM, Acute
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Syndrome (GBS) Acute ... complete paralysis of all ... than one after symptom ... the underlying pathophysiology
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
Activation of ACC ... BZD #withdrawal #pharmacology ... #pathophysiology ... diagnosis #signs #symptoms
Therapy for Benign Prostatic Hyperplasia (BPH) 
5 Alpha-Reductase inhibitors
 • Flnasterlde and dutasterlde act by reducing
and dutasterlde act ... reduced to improve symptoms ... reduction in the symptoms ... of BPH, such as acute ... #Medications #Pharmacology