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Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... than females Guillain-Barre ... bulbar muscles Guillain-Barre ... • Areflexia Guillain-Barre ... #Barre #Syndrome
Algorithm showing a stepwise approach to the assessment and investigation of a possible neuropathy. CIDP, chronic
electromyography; GBS, Guillain-Barré ... syndrome; HNPP, ... #Diagnosis #Neurology ... Algorithm #Evaluation #Differential
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Dyspnea - Differential ... failure - CAD/ACS ... Hepatopulmonary syndrome ... Myasthenia - Guillain ... Barre - ALS
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Inflammatory/AI: CIDP, Guillain-Barre ... Paraprotein-associated (POEMS syndrome ... Peripheral #Neuropathy #differential ... #diagnosis #causes ... #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Poliomyelitis, Guillain-Barre ... syndrome, Mononeuritis ... Lambert Eaton Syndrome ... Weakness #Causes #differential ... #diagnosis #neurology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Guillain-Barré syndrome ... Hyperthyroidism, Serotonin syndrome ... Testing #Causes #differential ... #diagnosis #table ... #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... complete paralysis of all ... SinaiBmoreIMRes #GBS #Guillain ... #Barre #Syndrome ... #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
Diagnosis: • ... Tethered cord • Guillain-Barre ... #differential # ... diagnosis #causes ... #neurology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... Diagnosis: • ... • Locked-in syndrome ... caseyalbin #PhysicalExam ... #diagnosis