13 results
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
intake, Diuretics ... -: Diuretics, Bartter ... Syndrome, Gitelman ... Syndrome Volume ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
intake, Diuretics ... -: Diuretics, Bartter ... Syndrome, Gitelman ... Syndrome Volume ... Diagnosis #Algorithm #Nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
acid, Liddle's Syndrome ... >20 mEq/24 h - Diuretics ... , Bartter's syndrome ... , Gitelman's syndrome ... Diagnosis #Algorithm #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... , Bartter's syndrome ... use), Gitelman's ... syndrome (mimics ... differential #diagnosis #nephrology
Gitelman Syndrome - Management
Treatment includes
 - Electrolyte replacement - K & Mg, preferably Cl salts
Gitelman Syndrome ... - Management Treatment ... Mg, preferably Cl ... hypokalemia, K sparing diuretics ... #Treatment #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... Inhibitors of Na+K+2Cl ... and nephrotic syndrome ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
• Low Urine Cl ... - Loop diuretics ... , Thiazide diuretics ... , Gitelman syndrome ... algorithm #diagnosis #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
loop or thiazide diuretics ... pressure: Active diuretic ... use, Bartter syndrome ... , Gitelman syndrome ... urine #Algorithm #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... with thiazide diuretic ... Surreptitious diuretic ... Rhabdomyolysis Treatment ... #nephrology #management
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
intake, Diuretics ... -: Diuretics, Bartter ... Syndrome, Gitelman ... Syndrome Euvolemic ... Diagnosis #Algorithm #Nephrology